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J Castrillo

 
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Jaime Castrillo Zapater is a professional cyclist from Spain. Subscribe to stay motivated with custom progress, segment and power goals.

KIAA0634

HGNC Approved Gene Symbol: ASTN2

Cytogenetic location: 9q33.1 Genomic coordinates (GRCh38): 9:116,423,111-117,415,056 (from NCBI)


TEXT

By sequencing clones obtained from a size-fractionated human brain cDNA library, Ishikawa et al. (1998) cloned ASTN2, which they designated KIAA0634. The deduced 1,321-amino acid protein shares a high degree of similarity with mouse astrotactin (ASTN1; 600904). RT-PCR detected ASTN2 in all tissues examined, with highest expression in brain, kidney, and testis, followed by ovary.

▼Mapping

By radiation hybrid analysis, Ishikawa et al. (1998) mapped the ASTN2 gene to chromosome 9. Garcia and Castrillo (2005) stated that the ASTN2 gene maps to chromosome 9q33.1.

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▼REFERENCES

  1. Garcia, J., Castrillo, J.-L. Identification of two novel human genes, DIPLA1 and DIPAS, expressed in placenta tissue. Gene 344: 241-250, 2005. [PubMed: 15656990, related citations] [Full Text]

  2. Ishikawa, K., Nagase, T., Suyama, M., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res. 5: 169-176, 1998. [PubMed: 9734811, related citations] [Full Text]

Patricia A. Hartz : 6/15/2009
mgross : 06/15/2009

ASTROTACTIN 2; ASTN2

KIAA0634

HGNC Approved Gene Symbol: ASTN2

Cytogenetic location: 9q33.1 Genomic coordinates (GRCh38): 9:116,423,111-117,415,056 (from NCBI)

TEXT

By sequencing clones obtained from a size-fractionated human brain cDNA library, Ishikawa et al. (1998) cloned ASTN2, which they designated KIAA0634. The deduced 1,321-amino acid protein shares a high degree of similarity with mouse astrotactin (ASTN1; 600904). RT-PCR detected ASTN2 in all tissues examined, with highest expression in brain, kidney, and testis, followed by ovary.

J Castrillo


By radiation hybrid analysis, Ishikawa et al. (1998) mapped the ASTN2 gene to chromosome 9. Garcia and Castrillo (2005) stated that the ASTN2 gene maps to chromosome 9q33.1.

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REFERENCES

  1. Garcia, J., Castrillo, J.-L. Identification of two novel human genes, DIPLA1 and DIPAS, expressed in placenta tissue. Gene 344: 241-250, 2005. [PubMed: 15656990] [Full Text: https://linkinghub.elsevier.com/retrieve/pii/S0378-1119(04)00609-2]

  2. Ishikawa, K., Nagase, T., Suyama, M., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res. 5: 169-176, 1998. [PubMed: 9734811] [Full Text: https://academic.oup.com/dnaresearch/article-lookup/doi/10.1093/dnares/5.3.169]

Patricia A. Hartz : 6/15/2009
J Castrillo
mgross : 06/15/2009